Deskripsi Pekerjaan
Are you ready to make a tangible impact on global health? AbbVie is seeking a highly skilled Senior Biotechnologist (Downstream) to join our world-class manufacturing and research team in Singapore. At AbbVie, we combine the focus and passion of a biotech startup with the expertise and resources of a global biopharmaceutical leader.
In this pivotal role, you will be at the forefront of innovative medicine production. You will lead downstream processing activities, ensuring that our life-changing therapies are manufactured to the highest quality standards. If you are passionate about bioprocessing excellence, process optimization, and working in a cutting-edge facility, this is the perfect opportunity to advance your career.
You will collaborate with cross-functional teams to resolve complex technical challenges, optimize purification workflows, and maintain strict compliance with cGMP regulations. We offer a dynamic work environment where your technical expertise will directly contribute to solving serious health issues for patients worldwide.
Tanggung Jawab
- Lead and oversee daily downstream processing operations, including chromatography, filtration, and viral clearance steps.
- Develop, validate, and troubleshoot purification processes to ensure high yield and product purity.
- Collaborate with engineering and quality assurance teams to manage equipment lifecycle and process scale-up.
- Draft, review, and maintain comprehensive technical documentation, including SOPs and batch production records.
- Identify and implement process improvements through continuous improvement methodologies to enhance operational efficiency.
- Ensure full adherence to cGMP, safety, and regulatory compliance standards during all phases of production.
- Provide technical leadership and mentorship to junior staff and laboratory technicians.
Kualifikasi
- Master’s or PhD degree in Biotechnology, Biochemistry, Chemical Engineering, or a related field.
- Minimum of 5-7 years of direct experience in downstream processing within the biopharmaceutical industry.
- In-depth knowledge of protein purification techniques, chromatography systems (e.g., ÄKTA), and TFF systems.
- Strong understanding of cGMP, FDA, and EMA regulatory requirements.
- Proven ability to troubleshoot complex process deviations and implement effective corrective actions.
- Excellent analytical, communication, and project management skills.
- Demonstrated experience working in a highly automated, fast-paced manufacturing environment.