Deskripsi Pekerjaan
Join Singapore's premier RNA therapeutics hub and advance the frontier of RNA-based medicines as a Scientist/Senior Scientist in RNA Analytical Development. At NATi, you'll contribute to groundbreaking research and development of next-generation RNA therapeutics, driving innovations that address critical unmet medical needs. This role offers the unique opportunity to work in a dynamic, cutting-edge environment where your expertise in analytical methodologies will directly impact the development of life-saving treatments. Collaborate with interdisciplinary teams of scientists and industry leaders to develop robust analytical strategies, ensuring the safety, efficacy, and quality of RNA therapeutics through advanced analytical techniques. Your work will shape the future of precision medicine while being part of Singapore's national initiative to establish leadership in RNA technology.
Tanggung Jawab
- Design, develop, and validate analytical methods for RNA therapeutics (e.g., mRNA, siRNA, ASO) using advanced techniques like HPLC, LC-MS, and qPCR
- Characterize physicochemical properties and stability profiles of RNA molecules to support formulation development
- Lead analytical investigations for product development, ensuring compliance with GMP and regulatory requirements
- Collaborate with process development and manufacturing teams to transfer analytical methods and support scale-up activities
- Maintain and troubleshoot complex analytical instrumentation, ensuring optimal performance and data integrity
- Document analytical protocols, reports, and regulatory submissions with precision and compliance
- Stay abreast of emerging RNA analytics technologies and implement best practices to enhance analytical capabilities
Kualifikasi
- PhD or Master's degree in Biochemistry, Molecular Biology, Chemistry, or related life sciences field
- Minimum 3-5 years of experience in RNA analytical development, with proven expertise in RNA characterization methods
- Strong hands-on experience with analytical instrumentation (HPLC, LC-MS, qPCR, capillary electrophoresis)
- Familiarity with GMP regulations and analytical method validation protocols
- Experience working in therapeutics development or biopharmaceutical industry preferred
- Excellent problem-solving skills with ability to troubleshoot complex analytical challenges
- Strong written and verbal communication skills for cross-functional collaboration
- Ability to work independently and manage multiple projects in a fast-paced environment